Trials & Filings

CymaBay Therapeutics Reports Results for Seladelpar in NASH

Results included minimal reductions in liver fat that were not significant when compared to placebo

CymaBay Therapeutics, Inc. announced 12-week topline results from an ongoing 52-week Phase 2b dose-ranging, paired liver biopsy study of seladelpar for the treatment of nonalcoholic steatohepatitis (NASH). Seladelpar is a potent and selective peroxisome proliferator-activated receptor delta (PPARδ) agonist currently in development for NASH and primary biliary cholangitis (PBC).   Treatment with seladelpar resulted in minimal reductions in liver fat that were not significant when compared to pl...

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